Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a form of encephalitis associated with antibodies against NR1 or NR2 subunits of the NMDA receptor.
Affected individuals typically develop prominent psychiatric symptoms, cognitive dysfunction, seizures, orofacial dyskinesias, and autonomic instability (8, 9).
Panel test:
● Autoantibodies:
o NDMA receptor antibody
o glutamic acid decarboxylase (GAD) antibody
o VGKC antibody
o aquaporin-4 receptor antibody
o aquaporin-4 receptor antibody
o LGI1 antibody
o CASPR2 antibody
o AMPA receptor antibody
o GABA receptor antibody
o MOG antibody
o Voltage-gated calcium channel (VGCC) antibody
o Acetylcholine receptor modulating antibody
o Titin antibody
o Striated muscled antibody
Reference:
1. Venkatesan A, Tunkel AR, Bloch KC, Lauring AS, Sejvar J, Bitnun A, Stahl J, Mailles A, Drebot M, Rupprecht CE, Yoder J, Cope JR, Wilson MR, Whitley RJ, Sullivan J, Granerod J, Jones C, Eastwood K, Ward KN, Durrheim DN, Solbrig MV, Guo-Dong L, Glaser CA, International Encephalitis Consortium. Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium. Clin Infect Dis. 2013; 57(8): 1114-28. PubMed
