EN

Eosinophilic Granulomatosis with Polyangiitis – EGPA

Eosinophilic Granulomatosis with Polyangiitis – EGPA

Also known Churg-strauss syndrome, is a scare autoimmune disorder that causes inflammation in small and medium sized blood vessels. The lungs, nose, sinuses, skins, skin, joints, nerves, intestinal tract, heart and kidney are injured. Most of the people have a history of asthma and allergies. Almost eosinophilia is in peripheral blood EGPA patients and there is glanulomas in the most tissue samples.

Panel Test:

● CBC with Automated Differential
● Urine analysis
● CRP and ESR
● ANCA or Anti-Neutrophil Cytoplasmic Antibody
● MPO/PR3 Antibodies


References

1. Puéchal X, Pagnoux C, Baron G, et al. Adding Azathioprine to Remission-Induction Glucocorticoids for Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss), Microscopic Polyangiitis, or Polyarteritis Nodosa Without Poor Prognosis Factors: A Randomized, Controlled Trial. Arthritis Rheumatol 2017; 69:2175.
2. Wechsler ME, Akuthota P, Jayne D, et al. Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis. N Engl J Med 2017; 376:1921.

دیدگاهتان را بنویسید

نشانی ایمیل شما منتشر نخواهد شد. بخش‌های موردنیاز علامت‌گذاری شده‌اند *