Hepatocellular carcinoma (HCC) tumors are among the most common in the world, particularly in populations with chronic viral hepatitis, such as those of Asian or sub-Saharan African ancestry. Most occur in individuals with chronic liver disease.
Panel test:
AFP total
AFP-L3%
DCP
Beta-Catenin
Hepatocyte specific antigen
Arginase 1
Cytokeratin 8,18 low molecular weight
Reticulin
Glypican 3
References
Guidelines
1. NCCN Clinical Practice Guidelines in Oncology, Hepatobiliary Cancers. 2.2018. National Comprehensive Cancer Network. Fort Washington, PA [Update: Jun 2018; Accessed: Sep 2018]
2. E. EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma. J Hepatol. 2018; 69(1): 182-236. PubMed
3. Kudo M, Matsui O, Izumi N, Iijima H, Kadoya M, Imai Y, Okusaka T, Miyayama S, Tsuchiya K, Ueshima K, Hiraoka A, Ikeda M, Ogasawara S, Yamashita T, Minami T, Yamakado K, Liver Cancer Study Group of Japan. JSH Consensus-Based Clinical Practice Guidelines for the Management of Hepatocellular Carcinoma: 2014 Update by the Liver Cancer Study Group of Japan. Liver Cancer. 2014; 3(3-4): 458-68. PubMed
4. Heimbach J, Kulik LM, Finn R, Sirlin CB, Abecassis M, Roberts LR, Zhu A, Murad H, Marrero J. AASLD guidelines for the treatment of hepatocellular carcinoma. Hepatology. 2017; PubMed
5. Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection. World Health Organization. Geneva, Switzerland [Accessed: Mar 2018]
6. Cong W, Bu H, Chen J, Dong H, Zhu Y, Feng L, Chen J, Committee G. Practice guidelines for the pathological diagnosis of primary liver cancer: 2015 update. World J Gastroenterol. 2016; 22(42): 9279-9287. PubMed
7. National Cancer Institute. Adult Primary Liver Cancer Treatement (PDQ)—Health Professional Version. Rockville, MD [Updated: Feb 2018; Accessed: Feb 2018]
