Cogan’s syndrome is a rare and chronic immune system mediated disease that mainly affects young people. This disorder characterized by interstitial keratitis, intraocular inflammation, audio vestibular symptoms and hearing loss. The cause of this syndrome is unknown but there were evidences that it relates to Chlamydia and Borrelia infections.
Panel Test:
● CBC with Automated Differential
● BUN and Creatinine
● Urine analysis for casts
● CRP and ESR
● ANCA or Anti-Neutrophil Cytoplasmic Antibody
● MPO/PR3 Antibodies
● ANA
● RPR
● HIV
References
1. St Clair EW, McCallum RM. Cogan’s syndrome. Curr Opin Rheumatol 1999; 11:47.
2. Jung DH, Nadol JB Jr, Folkerth RD, Merola JF. Histopathology of the Inner Ear in a Case with Recent Onset of Cogan’s Syndrome: Evidence for Vasculitis. Ann Otol Rhinol Laryngol 2016; 125:20.
3. Tayer-Shifman OE, Ilan O, Tovi H, Tal Y. Cogan’s syndrome–clinical guidelines and novel therapeutic approaches. Clin Rev Allergy Immunol 2014; 47:65.
