APS is an autoimmune disease which identified by thrombosis in arterial and venous. Antibodies from immune system attack phospholipids which are found in cell membranes. APS can lead to health problems, such as heart attack, kidney damage, deep vein thrombosis and pulmonary embolism. Also, it can cause multiple miscarriages and premature birth due to eclampsia that is a serious situation in pregnant women.
Panel Test:
o anti-β2GP1 antibodies, IgG and IgM;
o aCL antibodies, IgG and IgM
o Lupus Anticoagulant Reflexive Panel
o Cardiolipin Antibodies, IgG and IgM
o Beta-2 Glycoprotein 1 Antibodies, IgG and IgM
o High-Specificity Antiphospholipid Antibodies, IgG and IgM
o Phosphatidylserine and Prothrombin Antibodies, IgG and IgM
o Prothrombin Antibody, IgG
o Cardiolipin Antibody, IgA
o Beta-2 Glycoprotein 1 Antibody, IgA
o Dilute Russell Viper Venom Time (dRVVT)
o Hexagonal Phospholipid Neutralization
References
1. Lim W. Antiphospholipid syndrome. Hematology Am Soc Hematol Educ Program 2013; 2013:675.
