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Autoimmune pancreatitis

Autoimmune pancreatitis

Autoimmune pancreatitis is a rare systemic fibrotic inflammatory disorder that can affect the bile ducts, salivary glands, and retroperitoneal lymph nodes, in addition to the pancreas. Common symptoms of autoimmune pancreatitis include jaundice, weight loss, and mild abdominal pain (4, 5).
Panel test for Autoimmune pancreatitis
Initial testing
• Liver functional tests: May show an obstructive pattern
• Lipase: May be elevated, Nonspecific marker for pancreatic damage
• CBC: Useful in evaluation for malignancy, does not provide information for diagnosis of AIP

• Serum IgG4: ≥2-fold elevation of IgG4 highly suggestive of AIP
IgG4 elevated in ~66% of patients.
• CA19-9: elevated in 50% of patients with AIP. Also elevated in pancreatic cancer, but not specific.

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