AIED is a rare autoimmune syndrome identified by progressive hearing loss. Diagnosis is mostly based on clinical manifestations and response to immunosuppressive drugs. Some patients don’t respond to steroids and may be candidates for cytotoxic therapy.
Panel Test:
● Heat Shock Protein 70, IgG
● Anti-Neutrophil Cytoplasmic Antibody
● MPO/PR3 Antibodies
● Antinuclear Antibodies (ANA),
● Rheumatoid Factors, IgA, IgG, and IgM
● Thyroid Stimulating Hormone
● Free Thyroxine
● Treponema pallidum Antibody, IgG
● Borrelia burgdorferi Antibodies
● Hemoglobin A1c
● Human Immunodeficiency Virus (HIV)
● C-Reactive Protein
● Sedimentation Rate, Westergren (ESR)
References
1. Shamriz O, Tal Y, Gross M. Autoimmune Inner Ear Disease: Immune Biomarkers, Audiovestibular Aspects, and Therapeutic Modalities of Cogan’s Syndrome. J Immunol Res. 2018 Apr 23;2018:1498640.
