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Rhomatoid arthritis

Rhomatoid arthritis

Rheumatoid arthritis could be a chronic inflammatory disorder that may affect over just your joints. In some people, the condition can ruin a vast variety of body systems, including the skin, eyes, lungs, heart and blood vessels.

An autoimmune disorder, rheumatoid arthritis occurs when your immune system falsely attacks your own body’s tissues.

Although the wear-and-tear damage of osteoarthritis, rheumatoid arthritis affects the layers of your joints, causing a painful swelling that can cause to bone erosion and joint deformity.

The inflammation related to rheumatoid arthritis is what can damage other parts of the body as well. While new kinds of medications have improved treatment options dramatically, severe rheumatoid arthritis can still cause physical impairment.

Panel test

·        Antinuclear antibody (ANA)

·        Rheumatoid factor (RF)

·        Anti-cyclic citrullinated peptide (anti-CCP)

·        14.3.3 eta Protein

·        RF isotypes

·        Uric acid

·        HLA tissue typing

·        CBC and Erythrocyte sedimentation rate

·        C-reactive protein

·        Joint fluid tests

References

  1. Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JM, Hobbs K, Huizinga TW, Kavanaugh A, Kay J, Kvien TK, Laing T, Mease P, Ménard HA, Moreland LW, Naden RL, Pincus T, Smolen JS, Stanislawska-Biernat E, Symmons D, Tak PP, Upchurch KS, Vencovský J, Wolfe F, Hawker G. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 2010; 62(9): 2569-81. PubMed
  2. Choosing Wisely. An initiative of the ABIM Foundation. [Accessed: Apr 2019]
  3. van der Heijde D, van Mil AH, Aletaha D, Bingham CO, Burmester GR, Dougados M, Emery P, Felson D, Knevel R, Kvien TK, Landewé RB, Lukas C, McInnes I, Silman AJ, Smolen JS, Stanislawska-Biernat E, Zink A, Combe B. EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria Ann Rheum Dis. 2013; 72(4): 479-81. PubMed

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